Rather it is selected for in geographic regions where malaria is common (in a way similar to thalassemia), as heterozygous people have some resistance to the malarial Plasmodium parasite (heterozygote advantage).[2]These variable codes for amino acids are allowed because of modified bases in the first base of the anticodon of the tRNA, and the base pair formed is called a wobble base pair. The modified bases include inosine and the Non Watson Crick U G basepair.[3]Initiation or Start [edit]The s